High Pressure Reactions:
* hydrogenation & hydroformylation:1-2000L
Ultra low temperature Reaction: (-80℃) 500L~5000L/batch
Organometallic reagents:
* Alkyl lithium, 1500L/batch, many times (methyl lithium, n-butyl lithium, phenyl lithium)
* Grignard Reagent, 1500L/batch
Special Reactions
Hydrazines, 1500L/batch
Suzuki Coupling, 100L/batch
Fischer-Indole Synthesis, 2000L/batch
Ullmann (Cu or Pd catalysis) Coupling, 500L/batch
Vilsmeier Reaction, 500L/batch
R&D Capacity- Specialty
Chiral synthesis (Resolution and Asymmetric synthesis, Catalyst and Enzyme)
Selective conversion of enantiomers (Convert useless configuration to usable configuration)
Non-infringing Process Development
Impurity identification (TOF,GC-MS, LC-MS, NMR)
Mutagenic impurity research
Elemental Impurity research (ICP-MS)
Production Capacity
At least 20-35 GMP production line (with 10 HVAC system)
At least 350-500 Reactors (Total:350,000L-1000,000L)
Fully Equipped Facilities
Temperature: From -100℃ to 200℃
Pressure: From 50 Pa to 35 atm
Materials of Reactors: Glass-lined, Stainless Steel, Halar Coated.
Reactors Size: From 10L to 8000L
EHS Regulatory Compliance
Located in provincial chemical zone (Never stopped production in recent 5 years)
Production license (old products)/Production registration (new products)
Passed PSCI Inspection
Standardization (Class II) of safety production
VOCS compliance
ISO14001、OHSAS18001